Tissue microarrays in urology.

The TMA is a high-throughput technique to assess thousands of different cores of pathological tissue simultaneously using morphological and molecular analyses, e.g. immunohistochemistry and in situ hybridization, whilst maintaining an accurate and efficient method of identifying each specific section. Using this technique an economy in cutting and staining can also be used, with an unprecedented level of standardisation within one TMA experiment, as all the experimental conditions for all the cores are identical. It is now firmly established that the TMA can significantly accelerate the processing of very many tissue specimens, with excellent quality, good reliability and preservation of original tissue.